A chance meeting on a train to Tokyo sends two girls named Nana on a collision course with destiny! Nana "Hachi" Komatsu hopes that moving to Tokyo will help her make a clean start and leave her capricious love life behind her. Nana Osaki, who arrives in the city at the same time, has plans to score big in the world of rock'n'roll. Although these two young women come from different backgrounds, they quickly become best friends in a whirlwind world of sex, music, fashion, gossip and all-night parties!Nana K.'s perfect Tokyo life is crumbling around her.

She can't keep a job, she can't keep any money, and now it looks like she can't even keep her boyfriend! But luckily, a tasty nugget of gossip about Nana O.'s past love life helps Nana K. keep her mind off her own troubles. If she can play the role of cupid for her best friend, can Nana K. get closer to her own happy ending?