Sometimes your ancestors breathe through you. Sometimes, they call for vengeance...

Babs Dionne, doting grandmother and vicious crime matriarch, rules her small town with an iron fist. She controls the flow of drugs into its borders with the help of her loyal lieutenants, girlfriends since they were teenagers, and her eldest daughter, Lori, a former soldier struggling with addiction.

When a drug cartel discovers that its numbers are down in the area, they send a malevolent force, known only as The Man, to investigate.

At the same time, Babs's youngest daughter, Sis, has gone missing, which doesn't seem at all like a coincidence. In twenty-four hours, Sis will be found dead, and the whole town will seek shelter from Babs's wrath...